Publications

Journal Articles

Lewis JB, Hirschi KM, Arroyo JA, Bikman BT, Kooyman DL, Reynolds PR. Plausible Roles for RAGE in Conditions Exacerbated by Direct and Indirect (Secondhand) Smoke Exposure. Int J Mol Sci. 2017 Mar;18(3):E652.

Rose BJ, Seegmiller RE, Bridgewater LC, Kooyman DL. Collagen Mutant Mouse Models Provide an Important Tool to Study Osteoarthritis. Journal of Arthritis. 2016 Aug;5(5).

Kooyman DL, Rose BJ. A Tale of Two Joints: The Role of Matrix Metalloproteases in Cartilage Biology. Disease Markers. 2016 Jul:7 pages. <website>

Chavez EM, Mecham DK, Black CS, Graf JW, Steel SD, Wilhelm SK, Andersen KM, Mitchell JA, Macdonald JR, Hollis WR, et al. Malocclusion Model of Temporomandibular Joint Osteoarthritis in Mice With and Without Receptor for Advanced Glycation End Products. Archives of Oral Biology. 2016 May;69:47-62. <website>

Siebert M, Wilhelm SK, Kartchner JZ, Mecham D, Reynolds PR, Kooyman DL. Effect of Pharmacological Blocking of TLR-4 on Osteoarthritis in Mice. Journal of Arthritis. 2015 Sep;4(3).

Macdonald DW, Squires RS, Avery S, Adams J, Baer M, Cunningham CR, Heimann N, Kooyman DL, Seegmiller RE. Structural Variations in Articular Cartilage Matrix Are Associated with Early-Onset Osteoarthritis in the Spondyloepiphyseal Dysplasia Congenita (Sedc) Mouse. International Journal of Molecular Science. 2013 Aug;14:16515-16531.

Ricks ML, Farrell JT, Falk DJ, Holt DW, Rees M, Carr J, Williams T, Nichols BA, Bridgewater LC, Reynolds PR, et al. Osteoarthritis in Temporomandibular Joint of Col2a1 Mutant Mice. Archives of Oral Biology. 2013 Aug;58(9):1092-9.

Larkin DJ, Kartchner JZ, Doxey AS, Hollis WR, Rees JL, Wilhelm SK, Draper CS, Peterson DM, Jackson GG, Ingersoll C, et al. Inflammatory markers associated with osteoarthritis after destabilization surgery in young mice with and without Receptor for Advanced Glycation End-products (RAGE). Frontiers in Physiology. 2013 May;4:121-128.

Kooyman DL, Airmet K, Hinckley JD, Tree LT, Moss M, Blumell S, Ulicny K, Gustafson AK, Weed M, Theodosis R, et al. Construction of a Llama Bacterial Artificial Chromosome Library. Journal of Biomedicine and Biotechnology. 2012 Jun;2012(Article ID 371414):4.

Holt DW, Henderson ML, Stockdale CE, Farrell JT, Kooyman DL, Bridgewater LC, Seegmiller RE. Osteoarthritis-like changes in the heterozygous sedc mouse associated with the HtrA1-Ddr2-Mmp-13 degradative pathway: A new model of osteoarthritis. Osteoarthritis and Cartilage. 2012 Jan;20:430-439. <website>

Holt DW, Henderson ML, Stockdale CE, Ferrell JT, Kooyman DL, Bridgewater LC, Seegmiller RE. Osteoarthritis-like changes in the heterozygous sedc mouse associated with the HtrA1-Ddr2-Mmp-13 degradative pathway: a new model of osteoarthritis. Ostoeoarthritis and Cartilage. 2012 Jan;20:430-439. <website>

Thomson DM, Hancock CR, Evanson BG, Kenney SG, Mallan BB, Mongillo AD, Brown JD, Hepworth S, Fillmore N, Parcell AC, et al. Skeletal muscle dysfunction in muscle-specific LKB1 knockout mice. J Appl Physiol. 2010 Jun;108:1775-1785.

Abstract

Black CS, Crepeau PK, Sheffield ID, Macdonald JR, Wootton DJ, Baek M, Eggett DL, Reynolds PR, Kooyman DL. Identification of the Tidemark Line of Calcification in Osteoarthritic Cartilage Using a Stain for Alkaline Phosphatase. Osteoarthritis and Cartilage. 2015 Apr;23(Supplement 2):28. <website>

Kooyman DL, Reynolds PR, Wilhelm SK, Mecham D, Chavez EM, Kartchner JZ, Crepeau P, Andersen K, Vandruff J, Robinson M, et al. Blocking the receptor for advanced glycation end-products but not Toll-like receptor 4 attenuates the progression of OA. FASEB J. 2014 Apr;28:835.13.

Kooyman DL, Chavez EM, Mecham D, Wilhelm SK, Black CS, Mitchell J, Andersen K, Graf J, Macdonald J. Knocking out RAGE disrupts natural repair of condylar cartilage during osteoarthritis. FASEB J. 2014 Apr;28:835.14.

Kooyman DL, Andersen K, Black CS, Crepeau P, Kartchner JZ, Mecham D, Robinson M, Wilhelm SK, Chavez EM. TGF-β1 and HtrA1 interactive pathway in the molecular progression of osteoarthritis. FASEB J. 2014 Apr;28:1139.9.

Kooyman DL, Seegmiller RE, Wong P, Reece D, Hepworth J, Wilhelm SK, Mecham D. The role of TGFβ1 and HTRA1 in the pathogenesis of TMJ osteoarthritis. FASEB J. 2014 Apr;28:922.8.

Kooyman DL, Kartchner JZ, Peterson DM, Larkin DJ, Doxey AS, Hollis WR, Rees JL, Jackson GG, Wilhelm SK, Haynie SS, et al. The temporal expression of biomarkers associated with osteoarthritis after knee destabilizing surgery in mice with and without Receptor for Advanced Glycation End Products (RAGE). FASEB Journal. 2013 Apr:LB139.

Wilhelm SK, Doxey AS, Kartchner JZ, Vandruff J, Andersen K, Draper CS, Chavez E, Reynolds PR, Kooyman DL. Apoptosis Associated with Osteoarthritis is Attenuated in Mice Lacking the Receptor for Advanced Glycation End Products (RAGE). FASEB Journal. 2013 Apr;27:573.5.

Larkin DJ, Kartchner JZ, Doxey AS, Hollis WR, Rees JL, Wilhelm SK, Draper CS, Peterson DM, Jackson GC, Ingersoll C, et al. Inflammatory markers associated with osteoarthritis after destabilization surgery in mice with and without Receptor for Advanced Glycation End Products (RAGE). FASEB Journal. 2013 Apr;27:573.3.

Kooyman DL, Ricks ML, Falk DJ, Farrell J, Rees MB, Carr JM, Williams DT, Bridgewater LC, Seegmiller RE. Premature osteoarthritis in the temporomandibular joint of heterozygous disproportionate micromelia mice. Experimental Biology. 2012 Apr;26:LB 115.

Presentations

Sheffield ID, Nelson MA, Baek M, Coleman JM, Glenn S, Dorius B, Sanchez AE, Williams C, Rose BJ, Sheffield VC, et al. The role of chondrocyte primary cilia in osteoarthritis. Osteoarthritis Society International Meeting. Brussels, Belgium. 2016 .

Black CS, Crepeau PK, Sheffield ID, Macdonald JR, Wootton DJ, Baek M, Eggett DL, Reynolds PR, Kooyman DL. Identification of the Tidemark Line of Calcification in Osteoarthritic Cartilage Using a Stain for Alkaline Phosphatase. Osteoarthritis Society International Meeting. Boston, MA. 2015 .

Wilhelm SK, Mecham D, Chavez EM, Kartchner JZ, Crepeau P, Andersen K, Vandruff J, Robinson M, Christensen I, Taylor K, et al. Blocking the receptor for advanced glycation end-products but not Toll-like receptor 4 attenuates the progression of OA. Federation of American Societies for Experimental Biology. San Diego, CA. 2014 .

Chavez EM, Mecham D, Wilhelm SK, Black CS, Mitchell J, Andersen K, Graf J, Macdonald J, Reynolds PR, Kooyman DL. Knocking out RAGE disrupts natural repair of condylar cartilage during osteoarthritis. Federation of American Societies for Experimental Biology. San Diego, CA. 2014 .

Andersen K, Black CS, Crepeau P, Kartchner JZ, Mecham D, Robinson M, Wilhelm SK, Chavez EM, Kooyman DL. TGF-β1 and HtrA1 interactive pathway in the molecular progression of osteoarthritis. Federation of American Societies for Experimental Biology. San Diego, CA. 2014 .

Wong P, Reece D, Hepworth J, Wilhelm SK, Mecham D, Kooyman DL, Seegmiller RE. The role of TGFβ1 and HTRA1 in the pathogenesis of TMJ osteoarthritis. Federation of American Societies for Experimental Biology. San Diego, CA. 2014 .

Grose JH, Kooyman DL, Anderson J, Buckley A, Pezoa Cabeza Y, Emery H, Fullwood R, Hecht K, Jackson K, Jones E, et al. E. colin: A two circuit system for colin cancer detection. IGEM Regional Jamboree. Standford University. 2012 .

Ricks M, Falk DJ, Farrell JT, Rees MB, Carr JM, Williams DT, Kooyman DL, Bridgewater LC, Seegmiller RE. Premature osteoarthritis in the temporomandibular joint of heterozygous disproportionate micromelia mice. American Society for Biochemistry and Molecular Biology Annual Meeting. San Diego, California. 2012 .

Grose JH, Kooyman DL, Biggs M, Chamberlain C, Merrill M, Sabin D, Sabin M, Roberts J, Williams L, Alley A, et al. E. colinoscopy. Current topics in Chemistry. BYU. 2011 .

Grose JH, Kooyman DL, Biggs M, Chamberlain C, Merrill M, Sabin D, Sabin M, Roberts J, Williams L, Alley A, et al. Evolving a thermoswitch sensitive to narrow temperature shifts. IBE Western Regional Student Conference. Utah State University. 2011 .

Grose JH, Kooyman DL, Biggs M, Chamberlain C, Merrill M, Sabin D, Sabin M, Roberts J, Williams L, Alley A, et al. E. colinoscopy. IGEM Worldchampionship Jamboree. MIT. 2011 .

Grose JH, Kooyman DL, Biggs M, Chamberlain C, Merrill M, Sabin D, Sabin M, Roberts J, Williams L, Alley A, et al. E. colinoscopy. IGEM Regional Jamboree. Indianapolis. 2011 .

Thomson DM, Hancock CR, Evanson BG, Kenney SG, Malan BB, Mongillo AD, Brown JD, Hepworth S, Fillmore N, Parcell AC, et al. Muscle-specific LKB1 knockout leads to skeletal muscle dysfunction. FASEB Summer Research Conference- AMPK:Central Regulatory System in Metacolism & Growth. Kyoto, Japan. 2010 .